Fluorescent Sensor for PH Monitoring Based on an i-Motif- – Switching Aptamer Containing a Tricyclic Cytosine Analogue (tC)

There are cytosine-rich regions in the genome that bind protons with high specificity. Thus protonated C-rich sequence may undergo folding to tetraplex structures called i-motifs. Therefore, one can regard such specific C-rich oligonucleotides as aptamers that recognize protons and undergo conformat...

Full description

Bibliographic Details
Main Authors: Patrycja Bielecka, Bernard Juskowiak
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/10/18511