Rescue of retinal function by BDNF in a mouse model of glaucoma.

Vision loss in glaucoma is caused by progressive dysfunction of retinal ganglion cells (RGCs) and optic nerve atrophy. Here, we investigated the effectiveness of BDNF treatment to preserve vision in a glaucoma experimental model. As an established experimental model, we used the DBA/2J mouse, which...

Full description

Bibliographic Details
Main Authors: Luciano Domenici, Nicola Origlia, Benedetto Falsini, Elisa Cerri, Davide Barloscio, Carlotta Fabiani, Marco Sansò, Luca Giovannini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115579