Alpha-Synuclein Preformed Fibrils Induce Cellular Senescence in Parkinson’s Disease Models

Emerging evidence indicates that cellular senescence could be a critical inducing factor for aging-associated neurodegenerative disorders. However, the involvement of cellular senescence remains unclear in Parkinson’s disease (PD). To determine this, we assessed the effects of α-synuclein preformed...

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Bibliographic Details
Main Authors: Dinesh Kumar Verma, Bo Am Seo, Anurupa Ghosh, Shi-Xun Ma, Karina Hernandez-Quijada, Julie K. Andersen, Han Seok Ko, Yong-Hwan Kim
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
p21
Online Access:https://www.mdpi.com/2073-4409/10/7/1694