Application of 3R principles in small animal GLP testing of biomaterials

On the protection of animals used for scientific purposes, the EU Parliament adopted Directive 2010/63/EU. The essential factor is the 3R principle: Replacement, Reduction and Refinement. In 2013, the third amendment to the German Animal Welfare Act was revised and adapted to the European Directive....

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Bibliographic Details
Main Authors: Kischkel Sabine, Brietzke Andreas, Schmidt Wolfram, Eickner Thomas, Grabow Niels, Matschegewski Claudia
Format: Article
Language:English
Published: De Gruyter 2019-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2019-0084