Anti-DFS70 Antibodies Among Patient and Healthy Population Cohorts in China: Results From a Multicenter Training Program Showing Spontaneous Abortion and Pediatric Systemic Autoimmune Rheumatic Diseases Are Common in Anti-DFS70 Positive Patients

Anti-DFS70 Antibodies Among Patient and Healthy Population Cohorts in China: Results From a Multicenter Training Program Showing Spontaneous Abortion and Pediatric Systemic Autoimmune Rheumatic Diseases Are Common in Anti-DFS70 Positive Patients

ObjectiveAnti-DFS70 antibodies correlating with the nuclear dense fine speckled (DFS) pattern in the HEp-2 indirect immunofluorescence assay (IFA) are less common in patients with systemic autoimmune rheumatic disease (SARD) than in healthy subjects and their clinical associations remain elusive. We...

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Bibliographic Details
Main Authors: Bing Zheng, Zhiqing Wang, Rodrigo A. Mora, Aiping Liu, Chihui Li, Dengtao Liu, Fuying Zhai, Huiyuan Liu, Huiyun Gong, Jiaye Zhou, Jing Liu, Li Chen, Lijun Wu, Lin Yuan, Lina Ying, Loujian Jie, Meifang He, Meng Hao, Ping Xu, Qiuwei Lu, Shanshan Han, Shishi Chen, Shuimian Chen, Shunfei Zhu, Weihua Sun, Xiaoying Guo, Yajuan Chen, Yan Wang, Yemin Qu, Zhen Li, Zhenzhen Niu, Zhongyan Han, Edward K. L. Chan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
antinuclear antibodies
DFS70
pediatric rheumatic disease
spontaneous abortion
systemic autoimmune rheumatic disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.562138/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.562138/full

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