Fused-Ring Oxazolopyrrolopyridopyrimidine Systems with Gram-Negative Activity

Fused polyheterocyclic derivatives are available by annulation of a tetramate scaffold, and been shown to have antibacterial activity against a Gram-negative, but not a Gram-positive, bacterial strain. While the activity is not potent, these systems are structurally novel showing, in particular, a h...

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Bibliographic Details
Main Authors: Yiyuan Chen, Jonathan G. Moloney, Kirsten E. Christensen, Mark G. Moloney
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Antibiotics
Subjects:
Online Access:http://www.mdpi.com/2079-6382/6/1/2