Cytoplasmic 5’-3’ exonuclease Xrn1p is also a genome-wide transcription factor in yeast

Cytoplasmic 5’-3’ exonuclease Xrn1p is also a genome-wide transcription factor in yeast

The 5’ to 3’ exoribonuclease Xrn1 is a large protein involved in cytoplasmatic mRNA degradation as a critical component of the major decaysome. Its deletion in the yeast Saccharomyces cerevisiae is not lethal, but it has multiple physiological effects. In a previous study, our group showed that dele...

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Bibliographic Details
Main Authors: Daniel A Medina, Antonio eJordán-Pla, Gonzalo eMillán-Zambrano, Sebastián eChávez, Mordechai eChoder, José E Pérez-Ortín
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Genetics
Subjects:
mRNA decay
Transcription rate
nascent transcription
mRNA synthesis
mRNA stability.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00001/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00001/full

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