Associations between nitric oxide synthase genes and exhaled NO-related phenotypes according to asthma status.

BACKGROUND: The nitric oxide (NO) pathway is involved in asthma, and eosinophils participate in the regulation of the NO pool in pulmonary tissues. We investigated associations between single nucleotide polymorphisms (SNPs) of NO synthase genes (NOS) and biological NO-related phenotypes measured in...

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Bibliographic Details
Main Authors: Emmanuelle Bouzigon, Florent Monier, Mekki Boussaha, Nicole Le Moual, Hélène Huyvaert, Régis Matran, Sébastien Letort, Jean Bousquet, Isabelle Pin, Mark Lathrop, Francine Kauffmann, Florence Demenais, Rachel Nadif, EGEA Cooperative Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3348876?pdf=render