ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis

A well-established cascade of transcription factor (TF) activity orchestrates adipogenesis in response to chemical cues, yet how cell-intrinsic determinants of differentiation such as cell shape and/or seeding density inform this transcriptional program remain enigmatic. Here, we uncover a novel mec...

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Bibliographic Details
Main Authors: Daniel M Cohen, Kyoung-Jae Won, Nha Nguyen, Mitchell A Lazar, Christopher S Chen, David J Steger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06821