Combined immune checkpoint blockade and radiotherapy induces durable remission in relapsed natural killer/T-cell lymphoma: a case report and review of the literature

Combined immune checkpoint blockade and radiotherapy induces durable remission in relapsed natural killer/T-cell lymphoma: a case report and review of the literature

Abstract Background Extranodal natural killer/T-cell lymphoma is a rare, aggressive non-Hodgkin lymphoma that is treated upfront mostly with L-asparaginase containing regimens. Relapsed extranodal natural killer/T-cell lymphoma is associated with a poor prognosis, and there is no established standar...

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Bibliographic Details
Main Authors: Elizabeth McGehee, Hetalkumari Patel, Caroline Pearson, Keri Clements, Jesse Manuel Jaso, Weina Chen, Alexandra Callan, Neil Desai, Praveen Ramakrishnan Geethakumari
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Medical Case Reports
Subjects:
Extranodal NK/T-cell lymphoma (ENKL)
Immune checkpoint blockade
Radiation therapy
Pseudoprogression
PD-1
PD-L1
Online Access:https://doi.org/10.1186/s13256-021-02798-2

Internet

https://doi.org/10.1186/s13256-021-02798-2

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