E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1α/CXCR4.

OBJECTIVE: Endothelial-colony forming cells (ECFCs) can be readily expanded from human umbilical cord blood and can facilitate repair of endothelial injury. E-selectin and SDF-1α are produced following endothelial injury and can regulate endothelial progenitor homing. Mechanisms of vascular repair s...

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Bibliographic Details
Main Authors: Jie Sun, Yuhua Li, Gina M Graziani, Lionel Filion, David S Allan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3614942?pdf=render