TNFα inhibitors as targets for protective therapies in MSA: a viewpoint

TNFα inhibitors as targets for protective therapies in MSA: a viewpoint

Abstract Multiple system atrophy (MSA) is a unique and fatal α-synucleinopathy associated with oligodendroglial inclusions and secondary neurodegeneration affecting striatum, substantia nigra, pons, and cerebellum. The pathogenesis remains elusive; however, there is emerging evidence suggesting a pr...

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Bibliographic Details
Main Authors: Alain Ndayisaba, Kurt Jellinger, Thomas Berger, Gregor K. Wenning
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Neuroinflammation
Subjects:
TNFα
TNFα inhibitors
Multiple system atrophy
Neuroinflammation
Neurodegeneration
Disease-modifying treatment
Online Access:http://link.springer.com/article/10.1186/s12974-019-1477-5

Internet

http://link.springer.com/article/10.1186/s12974-019-1477-5

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