Therapeutic Targeting of the IGF Axis

The insulin like growth factor (IGF) axis plays a fundamental role in normal growth and development, and when deregulated makes an important contribution to disease. Here, we review the functions mediated by ligand-induced IGF axis activation, and discuss the evidence for the involvement of IGF sign...

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Bibliographic Details
Main Authors: Eliot Osher, Valentine M. Macaulay
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
IGF
Online Access:https://www.mdpi.com/2073-4409/8/8/895