The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition

FinO-domain proteins are bacterial RNA-binding proteins with a wide range of target specificities. Here, the authors employ UV CLIP-seq and show that minimal ProQ protein of Neisseria meningitidis binds to various small non-coding RNAs and mRNAs involved in virulence.

Bibliographic Details
Main Authors: Saskia Bauriedl, Milan Gerovac, Nadja Heidrich, Thorsten Bischler, Lars Barquist, Jörg Vogel, Christoph Schoen
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16650-6