Oct4 methylation-mediated silencing as an epigenetic barrier preventing Müller glia dedifferentiation in a murine model of retinal injury
Müller glia (MG) is the most abundant glial type in the vertebrate retina. Among its many functions, it is capable of responding to injury by dedifferentiating, proliferating and differentiating into every cell types lost to damage. This regenerative ability is notoriously absent in mammals. We have...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-11-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00523/full |