Short-Time Ocular Ischemia Induces Vascular Endothelial Dysfunction and Ganglion Cell Loss in the Pig Retina

Short-Time Ocular Ischemia Induces Vascular Endothelial Dysfunction and Ganglion Cell Loss in the Pig Retina

Visual impairment and blindness are often caused by retinal ischemia-reperfusion (I/R) injury. We aimed to characterize a new model of I/R in pigs, in which the intraocular pathways were not manipulated by invasive methods on the ocular system. After 12 min of ischemia followed by 20 h of reperfusio...

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Bibliographic Details
Main Authors: Jenia Kouchek Zadeh, Andreas Garcia-Bardon, Erik Kristoffer Hartmann, Norbert Pfeiffer, Wael Omran, Marion Ludwig, Andreas Patzak, Ning Xia, Huige Li, Adrian Gericke
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
I/R injury
retinal arterioles
endothelial dysfunction
ganglion cell loss
Online Access:https://www.mdpi.com/1422-0067/20/19/4685

Internet

https://www.mdpi.com/1422-0067/20/19/4685

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