In Vivo Evolution of Bacterial Resistance in Two Cases of Enterobacter aerogenes Infections during Treatment with Imipenem.

Infections caused by multidrug resistant (MDR) bacteria are a major concern worldwide. Changes in membrane permeability, including decreased influx and/or increased efflux of antibiotics, are known as key contributors of bacterial MDR. Therefore, it is of critical importance to understand molecular...

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Bibliographic Details
Main Authors: Nadège Philippe, Laure Maigre, Sébastien Santini, Elizabeth Pinet, Jean-Michel Claverie, Anne-Véronique Davin-Régli, Jean-Marie Pagès, Muriel Masi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4580588?pdf=render