A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo

A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo

Dendritic cell activation of CD4 T cells in the lymph node draining a site of infection or vaccination is widely considered the central event in initiating adaptive immunity. The accepted dogma is that this occurs by stimulating local activation and antigen acquisition by dendritic cells, with subse...

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Bibliographic Details
Main Authors: Hannah E. Scales, Gavin R. Meehan, Alan J. Hayes, Robert A. Benson, Emma Watson, Anne Walters, Michio Tomura, Eugene Maraskovsky, Paul Garside, Adriana Baz Morelli, James M. Brewer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
antigen processing and presentation
T cell activation
monocytes
subcapsular sinus macrophages
adjuvants
immunologic
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02684/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02684/full

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