Generation of reactive oxygen species by polyenylpyrroles derivatives causes DNA damage leading to G2/M arrest and apoptosis in human oral squamous cell carcinoma cells.

Generation of reactive oxygen species by polyenylpyrroles derivatives causes DNA damage leading to G2/M arrest and apoptosis in human oral squamous cell carcinoma cells.

Oral squamous cell carcinoma (OSCC) accounts for 5.8% of all malignancies in Taiwan and the incidence of OSCC is on the rise. OSCC is also a common malignancy worldwide and the five-year survival rate remains poor. Therefore, new and effective treatments are needed to control OSCC. In the present st...

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Bibliographic Details
Main Authors: Kuo-Feng Hua, Pei-Chun Liao, Zhanxiong Fang, Feng-Ling Yang, Yu-Liang Yang, Yi-Lin Chen, Yi-Chich Chiu, May-Lan Liu, Yulin Lam, Shih-Hsiung Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3695893?pdf=render

Internet

http://europepmc.org/articles/PMC3695893?pdf=render

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