Trimethyl Lock: A Stable Chromogenic Substrate for Esterases

p-Nitrophenyl acetate is the most commonly used substrate for detecting thecatalytic activity of esterases, including those that activate prodrugs in human cells. Thissubstrate is unstable in aqueous solution, limiting its utility. Here, a stable chromogenicsubstrate for esterases is produced by the...

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Bibliographic Details
Main Authors: Ronald T. Raines, Luke D. Lavis, Michael N. Levine
Format: Article
Language:English
Published: MDPI AG 2008-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/13/2/204/