Adaptive Thermogenesis Driving Catch-Up Fat Is Associated With Increased Muscle Type 3 and Decreased Hepatic Type 1 Iodothyronine Deiodinase Activities: A Functional and Proteomic Study

Adaptive Thermogenesis Driving Catch-Up Fat Is Associated With Increased Muscle Type 3 and Decreased Hepatic Type 1 Iodothyronine Deiodinase Activities: A Functional and Proteomic Study

Refeeding after caloric restriction induces weight regain and a disproportionate recovering of fat mass rather than lean mass (catch-up fat) that, in humans, associates with higher risks to develop chronic dysmetabolism. Studies in a well-established rat model of semistarvation-refeeding have report...

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Bibliographic Details
Main Authors: Celia Di Munno, Rosa Anna Busiello, Julie Calonne, Anna Maria Salzano, Jennifer Miles-Chan, Andrea Scaloni, Michele Ceccarelli, Pieter de Lange, Assunta Lombardi, Rosalba Senese, Federica Cioffi, Theo J. Visser, Robin P. Peeters, Abdul G. Dulloo, Elena Silvestri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
weight regain
catch-up fat
caloric restriction
thermogenesis
obesity
thrifty metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.631176/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.631176/full

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