Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants.
The most immediate and evident effect of mucosal exposure to semen in vivo is a local release of proinflammatory mediators accompanied by an influx of leukocytes into the female genital mucosa (FGM). The implication of such response in HIV-1 transmission has never been addressed due to limitations o...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-05-01
|
| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC5453613?pdf=render |