Abstract OR-4: Molecular Mechanism of Antibiotics Inhibiting Prokaryotic Translation

Abstract OR-4: Molecular Mechanism of Antibiotics Inhibiting Prokaryotic Translation

Background: About 50% of antibiotics used in the therapy of infectious diseases target bacterial 70S ribosomes. High resolution X-ray crystallographic studies allow us for determination of position of drug on the ribosome, but to elucidate the detailed molecular mechanism of inhibition it is necessa...

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Bibliographic Details
Main Authors: Andrey Konevega, Evgeny Pichkur, Alena Paleskava, Pavel Kasatsky, Elena Maksimova, Daria Vinogradova, Yury Polikanov, Alexander Myasnikov
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2019-06-01
Series:International Journal of Biomedicine
Subjects:
ribosome
antibiotics
structure
cryo-EM
Online Access:http://ijbm.org/articles/ijbm_2019_9_s1_or4.pdf

Internet

http://ijbm.org/articles/ijbm_2019_9_s1_or4.pdf

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