Discovering sparse transcription factor codes for cell states and state transitions during development

Computational analysis of gene expression to determine both the sequence of lineage choices made by multipotent cells and to identify the genes influencing these decisions is challenging. Here we discover a pattern in the expression levels of a sparse subset of genes among cell types in B- and T-cel...

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Bibliographic Details
Main Authors: Leon A Furchtgott, Samuel Melton, Vilas Menon, Sharad Ramanathan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/20488