Effect of WR-1065 on 6-hydroxydopamine-induced catalepsy and IL-6 level in rats

Objective(s): Neuroinflammation and oxidative stress play a key role in pathogenesis of Parkinson’s disease (PD). In the present study we investigated the effect of reactive oxygen species (ROS) scavenger WR-1065 on catalepsy and cerebrospinal fluid (CSF) level of interleukin 6(IL-6) and striatum su...

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Bibliographic Details
Main Authors: Afshin Kheradmand, Alireza Mohajjel Nayebi, Masoumeh Jorjani, Rasool Haddadi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Rat
SOD
Online Access:http://ijbms.mums.ac.ir/article_6933_87c7f8a83446a00bf92f957622769bc6.pdf