Synthesis of Enantiomeric Halolactones with Aromatic Ring, Their Anticancer Activity and Interactions with Biological Membranes

Studying the effect of chirality on the activity of tested compounds, we synthesized new series of the enantiomeric (ee = 98–100%) β-aryl-δ-halo-γ-lactones with defined configurations of stereogenic centers. [...]

Bibliographic Details
Main Authors: Witold Gładkowski, Aleksandra Pawlak, Aleksandra Włoch, Marcelina Mazur, Halina Kleszczyńska, Bożena Obmińska-Mrukowicz
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/22/1/47