Zinc finger and BTB domain-containing protein 46 is essential for survival and proliferation of acute myeloid leukemia cell line but dispensable for normal hematopoiesis

Abstract. Background. Zinc finger and BTB domain-containing protein 46 (Zbtb46) is a transcription factor identified in classical dendritic cells, and maintains dendritic cell quiescence in a steady state. Zbtb46 has been reported to be a negative indicator of acute myeloid leukemia (AML). We found...

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Bibliographic Details
Main Authors: Yuan-Yuan Liu, Fei-Fei Xiao, Bi-Jie Yang, Xi Li, Shuang-Nian Xu, Zhi-Wei Chen, Ping Li, Yong-Xiu Huang, Xue-Mei Fu, Xing-Qin Huang, Guang-Ling Zheng, Jie-Ping Chen, Yu Hou, Peng Lyu
Format: Article
Language:English
Published: Wolters Kluwer 2020-07-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000878