Development of immortalized Hertwig’s epithelial root sheath cell lines for cementum and dentin regeneration

Abstract Background Hertwig’s epithelial root sheath (HERS) is important in guiding tooth root formation by differentiating into cementoblasts through epithelial–mesenchymal transition (EMT) and inducing odontoblastic differentiation of dental papilla through epithelial–mesenchymal interaction (EMI)...

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Bibliographic Details
Main Authors: Xuebing Li, Sicheng Zhang, Zirui Zhang, Weihua Guo, Guoqing Chen, Weidong Tian
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-1106-8