Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro

Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro

Summary: The differentiation of human embryonic stem cells (hESCs) to hematopoietic lineages initiates with the specification of hemogenic endothelium, a transient specialized endothelial precursor of all blood cells. This in vitro system provides an invaluable model to dissect the emergence of hema...

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Bibliographic Details
Main Authors: Eva Garcia-Alegria, Sara Menegatti, Muhammad Z.H. Fadlullah, Pablo Menendez, Georges Lacaud, Valerie Kouskoff
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118303989

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http://www.sciencedirect.com/science/article/pii/S2213671118303989

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