Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining

Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining

An array of phenotypically diverse myeloid cells and macrophages (MC&M) resides in the tumor microenvironment, requiring multiplexed detection systems for visualization. Here we report an automated, multiplexed staining approach, named PLEXODY, that consists of five MC&M-related fluo...

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Bibliographic Details
Main Authors: Joshua Saylor, Zhaoxuan Ma, Helen S. Goodridge, Fangjin Huang, Anne E. Cress, Stephen J. Pandol, Stephen L. Shiao, Adriana C. Vidal, Lily Wu, Nicholas G. Nickols, Arkadiusz Gertych, Beatrice S. Knudsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
multiplex
immunofluorescence
immunohistochemistry
macrophage
myeloid
spatial profiling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02925/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02925/full

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