Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes
Objective: Biomarkers are needed to characterize heterogeneity within populations at risk for type 1 diabetes. The ratio of proinsulin to C-peptide (PI:C ratio), has been proposed as a biomarker of beta cell dysfunction and is associated with progression to type 1 diabetes. However, relationships be...
Main Authors: | Taylor M. Triolo, Laura Pyle, Sona Seligova, Liping Yu, Kimber Simmons, Peter Gottlieb, Carmella Evans-Molina, Andrea K. Steck |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Journal of Translational Autoimmunity |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589909021000095 |
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