IDH gene mutation in glioma

Glioma is one of the most common intracranial malignant tumors. Its development is associated with mutations in the isocitrate dehydrogenase (IDH) gene. IDH plays an important role in the tricarboxylic acid cycle, and when mutated, it can downregulate the expression of α-ketoglutarate and convert it...

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Bibliographic Details
Main Authors: Leping Liu, Xuejun Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Cancer Translational Medicine
Subjects:
Online Access:http://www.cancertm.com/article.asp?issn=2395-3977;year=2018;volume=4;issue=5;spage=129;epage=133;aulast=Liu