IDH gene mutation in glioma
Glioma is one of the most common intracranial malignant tumors. Its development is associated with mutations in the isocitrate dehydrogenase (IDH) gene. IDH plays an important role in the tricarboxylic acid cycle, and when mutated, it can downregulate the expression of α-ketoglutarate and convert it...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2018-01-01
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Series: | Cancer Translational Medicine |
Subjects: | |
Online Access: | http://www.cancertm.com/article.asp?issn=2395-3977;year=2018;volume=4;issue=5;spage=129;epage=133;aulast=Liu |