Minor groove binder distamycin remodels chromatin but inhibits transcription.

Minor groove binder distamycin remodels chromatin but inhibits transcription.

The condensed structure of chromatin limits access of cellular machinery towards template DNA. This in turn represses essential processes like transcription, replication, repair and recombination. The repression is alleviated by a variety of energy dependent processes, collectively known as "ch...

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Bibliographic Details
Main Authors: Parijat Majumder, Amrita Banerjee, Jayasha Shandilya, Parijat Senapati, Snehajyoti Chatterjee, Tapas K Kundu, Dipak Dasgupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23460895/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23460895/?tool=EBI

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