Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma

Natural medicinal plants are multi-targeted in nature and their anti-cancer activities are also complex and varied, thus requiring a more systematic analysis of their modes of action. Since the activation of signal transducer and activator of transcription 3 (STAT3) is often deregulated in non-small...

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Bibliographic Details
Main Authors: Jong Hyun Lee, Chulwon Kim, Seok-Geun Lee, Gautam Sethi, Kwang Seok Ahn
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cancers
Subjects:
ROS
GSH
Online Access:https://www.mdpi.com/2072-6694/10/11/427