Chronic Inhibition of FAAH Reduces Depressive-Like Behavior and Improves Dentate Gyrus Proliferation after Chronic Unpredictable Stress Exposure

Symptoms of depressive disorders such as anhedonia and despair can be a product of an aberrant adaptation to stress conditions. Chronic unpredictable stress model (CUS) can generate an increase in the activity of the hypothalamic-pituitary-adrenal axis (HPA) and induce a reduction of neurotrophin si...

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Main Authors: A. R. Tejeda-Martínez, J. M. Viveros-Paredes, G. V. Hidalgo-Franco, E. Pardo-González, V. Chaparro-Huerta, R. E. González-Castañeda, M. E. Flores-Soto
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2021/6651492