Macrophage Activation by Ursolic and Oleanolic Acids during Mycobacterial Infection

Macrophage Activation by Ursolic and Oleanolic Acids during Mycobacterial Infection

Oleanolic (OA) and ursolic acids (UA) are triterpenes that are abundant in vegetables, fruits and medicinal plants. They have been described as active moieties in medicinal plants used for the treatment of tuberculosis. In this study, we analyzed the effects of these triterpenes on macrophages infec...

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Bibliographic Details
Main Authors: Sonia López-García, Jorge Ismael Castañeda-Sanchez, Adelina Jiménez-Arellanes, Lilia Domínguez-López, Maria Eugenia Castro-Mussot, Javier Hernández-Sanchéz, Julieta Luna-Herrera
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Molecules
Subjects:
tuberculosis
oleanolic acid
ursolic acid
triterpenes
macrophages
nitric oxide (NO)
reactive oxygen species (ROS)
tumor necrosis factor (TNF-α)
transforming growth factor (TGF-β)
CD36
TGR5
Online Access:http://www.mdpi.com/1420-3049/20/8/14348

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http://www.mdpi.com/1420-3049/20/8/14348

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