Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma.

Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma.

BACKGROUND: MicroRNA-21 (miR-21) is up-regulated in tumor tissue of patients with malignant diseases, including hepatocellular carcinoma (HCC). Elevated concentrations of miR-21 have also been found in sera or plasma from patients with malignancies, rendering it an interesting candidate as serum/pla...

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Main Authors: Verena Bihrer, Oliver Waidmann, Mireen Friedrich-Rust, Nicole Forestier, Simone Susser, Jörg Haupenthal, Martin Welker, Ying Shi, Jan Peveling-Oberhag, Andreas Polta, Michael von Wagner, Heinfried H Radeke, Christoph Sarrazin, Jörg Trojan, Stefan Zeuzem, Bernd Kronenberger, Albrecht Piiper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3205002?pdf=render

Internet

http://europepmc.org/articles/PMC3205002?pdf=render

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