Identification of novel microRNAs in the sheep heart and their regulation in heart failure

Abstract Study of microRNA (miRNAs) using sheep models is limited due to lack of miRNA information. We therefore investigated oar-miRNAs and their regulation in an ovine model of heart failure (HF). Left ventricular (LV) tissue was collected from normal (Cont), HF (LV pacing @ ~220bpm for 13-days) a...

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Bibliographic Details
Main Authors: Lee Lee Wong, Miriam T. Rademaker, Eng Leng Saw, Kar Sheng Lew, Leigh J. Ellmers, Christopher J. Charles, Arthur Mark Richards, Peipei Wang
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08574-x