A 6-Nucleotide Regulatory Motif within the AbcR Small RNAs of Brucella abortus Mediates Host-Pathogen Interactions

In Brucella abortus, two small RNAs (sRNAs), AbcR1 and AbcR2, are responsible for regulating transcripts encoding ABC-type transport systems. AbcR1 and AbcR2 are required for Brucella virulence, as a double chromosomal deletion of both sRNAs results in attenuation in mice. Although these sRNAs are r...

Full description

Bibliographic Details
Main Authors: Lauren M. Sheehan, Clayton C. Caswell, Jean Celli, Yasuko Rikihisa
Format: Article
Language:English
Published: American Society for Microbiology 2017-06-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/3/e00473-17