The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor?

The master mitotic regulator, Polo-like kinase 1 (Plk1), is an essential gene for the correct execution of cell division. Plk1 has strong clinical relevance, as it is considered a bona fide cancer target, it is found overexpressed in a large collection of different cancer types and this tumoral over...

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Bibliographic Details
Main Author: Guillermo de Cárcer
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/10/3/208