The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor?
The master mitotic regulator, Polo-like kinase 1 (Plk1), is an essential gene for the correct execution of cell division. Plk1 has strong clinical relevance, as it is considered a bona fide cancer target, it is found overexpressed in a large collection of different cancer types and this tumoral over...
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Format: | Article |
Language: | English |
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MDPI AG
2019-03-01
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Series: | Genes |
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Online Access: | http://www.mdpi.com/2073-4425/10/3/208 |