Tracking cefoperazone/sulbactam resistance development in vivo in A. baumannii isolated from a patient with hospital-acquired pneumonia by whole-genome sequencing

Cefoperazone/sulbactam has been shown to be efficacious for the treatment of infections caused by Acinetobacter baumannii; however, the mechanism underlying resistance to this synergistic combination is not well understood. In the present study, two A. baumannii isolates, AB1845 and AB2092, were iso...

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Bibliographic Details
Main Authors: Xiaofen Liu, Huajun Zheng, Weipeng Zhang, Zhen Shen, Miao Zhao, Yuancheng Chen, Li Sun, Jun Shi, Jing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01268/full