STAT3 Promotes Invasion and Aerobic Glycolysis of Human Oral Squamous Cell Carcinoma via Inhibiting FoxO1

STAT3 Promotes Invasion and Aerobic Glycolysis of Human Oral Squamous Cell Carcinoma via Inhibiting FoxO1

Signal transducer and activator of transcription 3 (STAT3), a previously accepted tumor-promoting protein in various malignancies, plays a key role in the process of cancer glycolysis. However, the role and potential mechanism of STAT3 in aerobic glycolysis and progression of oral squamous cell carc...

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Bibliographic Details
Main Authors: Min Zheng, Ming-xin Cao, Xiang-hua Yu, Li Li, Ke Wang, Sha-sha Wang, Hao-fan Wang, Ya-Jie Tang, Ya-ling Tang, Xin-hua Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
STAT3
FoxO1
aerobic glycolysis
EMT
OSCC
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01175/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01175/full

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