IgE Epitopes of the House Dust Mite Allergen Der p 7 Are Mainly Discontinuous and Conformational

IgE Epitopes of the House Dust Mite Allergen Der p 7 Are Mainly Discontinuous and Conformational

BackgroundSeveral studies indicate that Der p 7 is an important and clinically relevant allergen of Dermatophagoides pteronyssinus which should be included in vaccines for treatment of house dust mite (HDM) allergy. Aim of this study was to characterize the IgE epitopes of Der p 7.MethodsRecombinant...

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Bibliographic Details
Main Authors: Mirela Curin, Huey-Jy Huang, Tetiana Garmatiuk, Sandra Gutfreund, Yvonne Resch-Marat, Kuan-Wei Chen, Kerstin Fauland, Walter Keller, Petra Zieglmayer, René Zieglmayer, Patrick Lemell, Friedrich Horak, Wolfgang Hemmer, Margarete Focke-Tejkl, Sabine Flicker, Susanne Vrtala, Rudolf Valenta
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
allergy
allergen
allergen structure
house dust mite allergy
Der p 7
IgE epitope mapping
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.687294/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.687294/full

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