Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial

Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial

Abstract Background Gabapentin has shown efficacy in the treatment of chronic neuropathic or mixed pain in adults. Although pediatric pain specialists have extensive experience with gabapentin for the treatment of neuropathic pain, its use is off-label. Its efficacy and safety in this context have n...

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Bibliographic Details
Main Authors: Thomas G. de Leeuw, Laura Mangiarini, Rebecca Lundin, Florentia Kaguelidou, Tjitske van der Zanden, Oscar Della Pasqua, Dick Tibboel, Adriana Ceci, Saskia N. de Wildt, on behalf of the GAPP consortium
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Trials
Subjects:
Gabapentin
Neuropathic pain
Children
Pharmacokinetics
Online Access:http://link.springer.com/article/10.1186/s13063-018-3169-3

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http://link.springer.com/article/10.1186/s13063-018-3169-3

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