Precision multidimensional assay for high-throughput microRNA drug discovery

Progress in drug discovery can be hampered by a limited exploration of chemical space and the difficulty in assessing the full range of drug candidates’ effects on living cells. Here the authors describe a cell-based assay to distinguish between off-target and specific effects of candidate compounds...

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Bibliographic Details
Main Authors: Benjamin Haefliger, Laura Prochazka, Bartolomeo Angelici, Yaakov Benenson
Format: Article
Language:English
Published: Nature Publishing Group 2016-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10709