Aspartic acid70 in the HLA-DRB1 chain and shared epitope alleles partially explain the high prevalence of autoimmunity in Mexicans

Aspartic acid70 in the HLA-DRB1 chain and shared epitope alleles partially explain the high prevalence of autoimmunity in Mexicans

Introduction: Autoimmune thyroid disease (AITD) is the most common autoimmune disorder worldwide. Remarkably, it is commonly accompanied by other autoimmune diseases, such as rheumatoid arthritis (RA). The immunopathogenic mechanisms behind the coexistence of these disorders are still not completely...

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Bibliographic Details
Main Authors: Luis Francisco Valdés-Corona, Susana Hernández-Doño, Tatiana Sofia Rodríguez-Reyna, Rafael García-Silva, Juan Jakez, Monica Escamilla-Tilch, Guadalupe Lima, Luis Llorente, Carlos Pineda, Edmond Yunis, Julio Granados
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Translational Autoimmunity
Subjects:
Multiple autoimmunities
Rheumatoid arthritis
Autoimmune thyroid disease
Graves’ disease
Hashimoto’s disease
Shared epitope
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909020300241

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http://www.sciencedirect.com/science/article/pii/S2589909020300241

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