Species-wide whole genome sequencing reveals historical global spread and recent local persistence in Shigella flexneri

Species-wide whole genome sequencing reveals historical global spread and recent local persistence in Shigella flexneri

Shigella flexneri is the most common cause of bacterial dysentery in low-income countries. Despite this, S. flexneri remains largely unexplored from a genomic standpoint and is still described using a vocabulary based on serotyping reactions developed over half-a-century ago. Here we combine whole g...

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Bibliographic Details
Main Authors: Thomas R Connor, Clare R Barker, Kate S Baker, François-Xavier Weill, Kaisar Ali Talukder, Anthony M Smith, Stephen Baker, Malika Gouali, Duy Pham Thanh, Ishrat Jahan Azmi, Wanderley Dias da Silveira, Torsten Semmler, Lothar H Wieler, Claire Jenkins, Alejandro Cravioto, Shah M Faruque, Julian Parkhill, Dong Wook Kim, Karen H Keddy, Nicholas R Thomson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-08-01
Series:eLife
Subjects:
Shigella
dysentery
genomic
pathogen evolution
Online Access:https://elifesciences.org/articles/07335

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