Oral Formulation of Angiotensin-(1-7) Promotes Therapeutic Actions in a Model of Eosinophilic and Neutrophilic Asthma

Oral Formulation of Angiotensin-(1-7) Promotes Therapeutic Actions in a Model of Eosinophilic and Neutrophilic Asthma

The presence of eosinophils and neutrophils in the lungs of asthmatic patients is associated with the severity of the disease and resistance to corticosteroids. Thus, defective resolution of eosinophilic and neutrophilic inflammation is importantly related to exacerbation of asthma. In this study, w...

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Bibliographic Details
Main Authors: Giselle Santos Magalhães, Juliana Fabiana Gregório, Arthur Tonani Pereira Cançado Ribeiro, Isis Felippe Baroni, Ana Victoria de Oliveira Vasconcellos, Gabriela Pansanato Nakashima, Isabel Fusaro Aguiar Oliveira, Natália Alves de Matos, Thalles de Freitas Castro, Frank Silva Bezerra, Ruben D. Sinisterra, Vanessa Pinho, Mauro Martins Teixeira, Robson Augusto Souza Santos, Maria Glória Rodrigues-Machado, Maria José Campagnole-Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
resolution of inflammation
eosinophilic inflammation
neutrophilic inflammation
allergic lung inflammation
LPS
renin–angiotensin system 4
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.557962/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.557962/full

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