Prokaryotic caspase homologs: phylogenetic patterns and functional characteristics reveal considerable diversity.

Caspases accomplish initiation and execution of apoptosis, a programmed cell death process specific to metazoans. The existence of prokaryotic caspase homologs, termed metacaspases, has been known for slightly more than a decade. Despite their potential connection to the evolution of programmed cell...

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Bibliographic Details
Main Authors: Johannes Asplund-Samuelsson, Birgitta Bergman, John Larsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23185476/?tool=EBI