Protein citrullination as a source of cancer neoantigens

Protein citrullination as a source of cancer neoantigens

Background Citrulline post-translational modification of proteins is mediated by protein arginine deiminase (PADI) family members and has been associated with autoimmune diseases. The role of PADI-citrullinome in immune response in cancer has not been evaluated. We hypothesized that PADI-mediated ci...

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Bibliographic Details
Main Authors: Makoto Kobayashi, Jody Vykoukal, Hiroyuki Katayama, James Long, Jinsong Liu, Ehsan Irajizad, Alejandro Sevillarno, Nikul Patel, Xiangying Mao, Leona Rusling, Yining Cai, Fuchung Hsiao, Chuan-Yih Yu, Franscisco Esteva, Johannes Fahrmann, Sam Hanash
Format: Article
Language:English
Published: BMJ Publishing Group 2021-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/6/e002549.full

Internet

https://jitc.bmj.com/content/9/6/e002549.full

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